No inside presence, poor guard play, no shooters and recurring poor fundamentals + young team on the road - recipe for a pummeling.
Creighton is basically the polar opposite in all those categories. And, as others have noted, they seem to have a system and all the players understand the system, knowing where they and their teammates are supposed to be.
When an NU guard drives into the paint, the other 4 seem to be glued to a spot - never seems to be much effort or understanding of how to find an open area.
Also, as was pointed out previously, could they not figure out that Groselle is left-handed? Every time in the post, they positioned themselves to take away his weak hand. Maybe he can go to the right, but I would think you would at least try to force him that way.